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pentobarbital will decrease the level or impact of fentanyl by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of fentanyl with CYP3A4 inducers may lead to the lessen in fentanyl plasma concentrations, deficiency of efficacy or, probably, improvement of the withdrawal syndrome inside of a affec

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